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Product Details:
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Name: | Telmisartan | Appearance: | White Powder |
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CAS: | 144701-48-4 | Package: | Aluminum Foil Bag |
Production Capacity: | 500 Kilogram/month | Storage: | Kept In A Cool,dry And Ventilated Place |
Purity: | 99% | MF: | C33H30N4O2 |
High Light: | Telmisartan Pharma Intermediates,144701-48-4 Pharma Intermediates,C33H30N4O2 Pharma Intermediates |
Telmisartan CAS144701-48-4 Telmisartan Good Quality Telmisartan Low Price 99% Raw Materials Telmisartan
Prodcut name | Telmisartan |
MOQ | 1kg |
CAS No. | 144701-48-4 |
Appearance | crystalline powder |
Molecular Formula | C33H30N4O2 |
Assay | 99% |
Application | Pharma grade or research purpose |
Packing | As per your request |
Storage | Preserve in tight, light-resistant containers in a cool place |
Remarks | NA |
Custom synthesis | Available |
Supply Ability | 500kg/month |
Description:
Telmisartan, 4'-[(1,4'-dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid (Micardis), does not appear to bear any structuralrelationship to this class, but there is actually a great dealof overlap in the chemical architecture with other agents.
The first, and most significant, difference is the replacement of the acidic tetrazole system with a simple carboxylic acid. This acid, like the tetrazole, plays a role in receptor binding.
The second difference is the lack of a carboxylic acid near the imidazolenitrogen that also contributes to receptor binding.As with irbesartan, however, there is not a need for this groupto be acidic but, rather, to be one that participates in receptorbinding. The second ring, much like a purine basein deoxyribonucleic acid (DNA), can hydrogen bond with theangiotensin II receptor.
Usage:
Used alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus.
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