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Apixaban Pharmaceutical Intermediate CAS 503612-47-3 For Anticoagulants

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Apixaban Pharmaceutical Intermediate CAS 503612-47-3 For Anticoagulants

Apixaban Pharmaceutical Intermediate CAS 503612-47-3 For Anticoagulants
Apixaban Pharmaceutical Intermediate CAS 503612-47-3 For Anticoagulants

Large Image :  Apixaban Pharmaceutical Intermediate CAS 503612-47-3 For Anticoagulants Get Best Price

Product Details:
Place of Origin: China
Brand Name: germax
Certification: GMP
Model Number: Apixaban
Payment & Shipping Terms:
Minimum Order Quantity: 100 grams
Price: Negotiable
Packaging Details: 1kg/bag or 25kgs/drum
Delivery Time: within 3 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 500kgs/month
Detailed Product Description
Name: Apixaban Cas: 503612-47-3
Mf: C25h25n5o4 Content: 99%
Appearance: White Powder Package: 5kgs/bottle
Quality Standard: CP,USP
High Light:

Apixaban Pharmaceutical Intermediate

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CAS 503612-47-3 Pharmaceutical Intermediate

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Anticoagulants Pharmaceutical Intermediate

Factory Price 99% Apixaban Manufacturer CAS 503612-47-3 For Anticoagulants

Description

Apixaban is a highly selective, reversible, and direct inhibitor of Human Factor X and Rabbit Factor X with Ki of 0.08 nM and 0.17 nM, respectively. Apixaban exhibits a high degree of potency, selectivity, and efficacy on Factor X with Ki of 0.08 nM and 0.17 nM for Human Factor X and Rabbit Factor X, respectively. In vitro, Apixaban prolongs the clotting times of normal human plasma with theconcentrations (EC2x) of 3.6 μM, 0.37 μM, 7.4 μM, and 0.4 μM, which are required respectively to double the prothrombin time (PT),modified prothrombin time (mPT), activated partial thromboplastin time (APTT) and HepTest. Besides, Apixaban shows the highestpotency in human and rabbit plasma, but less potency in rat and dog plasma in both the PT and APTT assays.


Quick Details

Product Name:Apixaban
Cas No : 503612-47-3
CB No: CB51508586
Molecular formula:C25H25N5O4
Molecular weight: 459.504
Assay: 99%min
Packing: 1kg/bag or 25kgs/drum or Against customer'demand



Specifications

 

Name Apixaban
Synonyms 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
Brand Salus
Molecular Formula C25H25N5O4
Molecular Weight 459.50
CAS Registry Number 503612-47-3

 

 

 

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